4 ms·

Citation needed

• bobmcnamara 2y ago
  "Regular use of paracetamol, but not ibuprofen, was associated with a significantly higher risk of new-onset dementia in the old population, regardless of genetic risks of dementia." https://pubmed.ncbi.nlm.nih.gov/37633120/ https://pubmed.ncbi.nlm.nih.gov/37633120/
  • stephc_int13 2y ago
    Paracetamol is the default painkiller for most people, I would suspect that regular use means some kind of inflammation. I would not find surprising that chronic headache could be correlated with risk of dementia.
    • boomlinde 2y ago
      The study however found no such association between regular ibuprofen use and dementia. Not sure what compels people to go all "I have no idea what the supposed results of the study are but my amateur intuition about it tells me it's wrong".
  • jodleif 2y ago
    Thanks!
  • crackedbassoon 2y ago
    That paper is extremely weak. Look at the confidence intervals surrounding the hazard ratios. There is almost no effect for paracetamol and the difference between paracetamol and ibuprofen is negligible. If this is the evidence, I’m not concerned.