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Paracetamol is an anticholinergic isn’t it? It’s bad for your brain and its usage is associated with dementia.
by drivebyhooting 2y ago
Paracetamol is an anticholinergic isn’t it? It’s bad for your brain and its usage is associated with dementia.
- toxik 2y agoAre you really suggesting paracetamol causes dementia?
- jodleif 2y agoCitation needed
- bobmcnamara 2y ago"Regular use of paracetamol, but not ibuprofen, was associated with a significantly higher risk of new-onset dementia in the old population, regardless of genetic risks of dementia." https://pubmed.ncbi.nlm.nih.gov/37633120/ https://pubmed.ncbi.nlm.nih.gov/37633120/
- stephc_int13 2y agoParacetamol is the default painkiller for most people, I would suspect that regular use means some kind of inflammation. I would not find surprising that chronic headache could be correlated with risk of dementia.
- boomlinde 2y agoThe study however found no such association between regular ibuprofen use and dementia. Not sure what compels people to go all "I have no idea what the supposed results of the study are but my amateur intuition about it tells me it's wrong".
- jodleif 2y agoThanks!
- crackedbassoon 2y agoThat paper is extremely weak. Look at the confidence intervals surrounding the hazard ratios. There is almost no effect for paracetamol and the difference between paracetamol and ibuprofen is negligible. If this is the evidence, I’m not concerned.
- jprival 2y ago> Paracetamol is an anticholinergic isn’t it? No, per https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2008.01737.x https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.15... Can’t say whether it’s good for your brain otherwise.