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By the Betteridge's law of headlines [0], the answer should be "no". [0] - https://en.m.wikipedia.org/wiki/Betteridge%27s_law_of_headlines https://en.m.wikiped

by zx8080 2y ago

By the Betteridge's law of headlines [0], the answer should be "no". [0] - https://en.m.wikipedia.org/wiki/Betteridge%27s_law_of_headlines https://en.m.wikipedia.org/wiki/Betteridge%27s_law_of_headli...

lhl 2y ago
And yet the wide-ranging neuroprotective effects of ketones have been quite well documented... Poff, Angela M., Jong M. Rho, and Dominic P. D’Agostino. “Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives.” Frontiers in Neuroscience 13 (2019). https://doi.org/10.3389/fnins.2019.01041 https://doi.org/10.3389/fnins.2019.01041. Bernini, Adriano, Mojgan Masoodi, Daria Solari, John-Paul Miroz, Laurent Carteron, Nicolas Christinat, Paola Morelli, et al. “Modulation of Cerebral Ketone Metabolism Following Traumatic Brain Injury in Humans.” Journal of Cerebral Blood Flow & Metabolism, October 24, 2018, 0271678X18808947. https://doi.org/10.1177/0271678X18808947 https://doi.org/10.1177/0271678X18808947. McDonald, Tanya, Mackenzie Cervenka, Tanya J. W. McDonald, and Mackenzie C. Cervenka. “The Expanding Role of Ketogenic Diets in Adult Neurological Disorders.” Brain Sciences 8, no. 8 (August 8, 2018): 148. https://doi.org/10.3390/brainsci8080148 https://doi.org/10.3390/brainsci8080148. Koppel, Scott J., and Russell H. Swerdlow. “Neuroketotherapeutics: A Modern Review of a Century-Old Therapy.” Neurochemistry International 117 (July 2018): 114–25. https://doi.org/10.1016/j.neuint.2017.05.019 https://doi.org/10.1016/j.neuint.2017.05.019. White, Hayden, Karthik Venkatesh, and Bala Venkatesh. “Systematic Review of the Use of Ketones in the Management of Acute and Chronic Neurological Disorders.” Journal of Neurology and Neuroscience 08, no. 02 (2017). https://doi.org/10.21767/2171-6625.1000188 https://doi.org/10.21767/2171-6625.1000188. Prins, Mayumi L., and Joyce H. Matsumoto. “The Collective Therapeutic Potential of Cerebral Ketone Metabolism in Traumatic Brain Injury.” Journal of Lipid Research 55, no. 12 (December 2014): 2450–57. https://doi.org/10.1194/jlr.R046706 https://doi.org/10.1194/jlr.R046706.
mathgeek 2y ago
The answer is more often “yes” when referring to academic studies, as your Wikipedia source calls out via a reference to https://gwern.net/doc/statistics/2016-cook.pdf https://gwern.net/doc/statistics/2016-cook.pdf > A 2016 study of a sample of academic journals (not news publications) that set out to test Betteridge's law and Hinchliffe's rule (see below) found that few titles were posed as questions and of those, few were yes/no questions and they were more often answered "yes" in the body of the article rather than "no". Thankfully the underlying study doesn’t pose a question, and the article we are discussing here is an academic hypothesis more than news.

by zx8080 2y ago

lhl 2y ago

And yet the wide-ranging neuroprotective effects of ketones have been quite well documented... Poff, Angela M., Jong M. Rho, and Dominic P. D’Agostino. “Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives.” Frontiers in Neuroscience 13 (2019). https://doi.org/10.3389/fnins.2019.01041 https://doi.org/10.3389/fnins.2019.01041. Bernini, Adriano, Mojgan Masoodi, Daria Solari, John-Paul Miroz, Laurent Carteron, Nicolas Christinat, Paola Morelli, et al. “Modulation of Cerebral Ketone Metabolism Following Traumatic Brain Injury in Humans.” Journal of Cerebral Blood Flow & Metabolism, October 24, 2018, 0271678X18808947. https://doi.org/10.1177/0271678X18808947 https://doi.org/10.1177/0271678X18808947. McDonald, Tanya, Mackenzie Cervenka, Tanya J. W. McDonald, and Mackenzie C. Cervenka. “The Expanding Role of Ketogenic Diets in Adult Neurological Disorders.” Brain Sciences 8, no. 8 (August 8, 2018): 148. https://doi.org/10.3390/brainsci8080148 https://doi.org/10.3390/brainsci8080148. Koppel, Scott J., and Russell H. Swerdlow. “Neuroketotherapeutics: A Modern Review of a Century-Old Therapy.” Neurochemistry International 117 (July 2018): 114–25. https://doi.org/10.1016/j.neuint.2017.05.019 https://doi.org/10.1016/j.neuint.2017.05.019. White, Hayden, Karthik Venkatesh, and Bala Venkatesh. “Systematic Review of the Use of Ketones in the Management of Acute and Chronic Neurological Disorders.” Journal of Neurology and Neuroscience 08, no. 02 (2017). https://doi.org/10.21767/2171-6625.1000188 https://doi.org/10.21767/2171-6625.1000188. Prins, Mayumi L., and Joyce H. Matsumoto. “The Collective Therapeutic Potential of Cerebral Ketone Metabolism in Traumatic Brain Injury.” Journal of Lipid Research 55, no. 12 (December 2014): 2450–57. https://doi.org/10.1194/jlr.R046706 https://doi.org/10.1194/jlr.R046706.

mathgeek 2y ago

The answer is more often “yes” when referring to academic studies, as your Wikipedia source calls out via a reference to https://gwern.net/doc/statistics/2016-cook.pdf https://gwern.net/doc/statistics/2016-cook.pdf > A 2016 study of a sample of academic journals (not news publications) that set out to test Betteridge's law and Hinchliffe's rule (see below) found that few titles were posed as questions and of those, few were yes/no questions and they were more often answered "yes" in the body of the article rather than "no". Thankfully the underlying study doesn’t pose a question, and the article we are discussing here is an academic hypothesis more than news.