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Turns out, myopia isn't hereditary. It has to do with dopamine interactions and the retina receiving outdoor lighting. When there is insufficient outdoor lighti

by hosh 2y ago

Turns out, myopia isn't hereditary. It has to do with dopamine interactions and the retina receiving outdoor lighting. When there is insufficient outdoor lighting, the retina starts growing in a different shape, leading to myopia. Just let the kids play outside. I don't know if going outside more often will reverse it. Astigmatism, on the other hand, may be hereditary.

lucb1e 2y ago
> Just let I don't know about you, but in my case that would have been "just push". RCT1+2 was a lot more fun and even if I would play with the (often mean) village kids, they too were more into video games than ball games, albeit more something like Postal (rated for mature audiences, like ten years older than we were). There was some voluntary playing outside as well as inverse curfews imposed to make sure we don't only game and watch Pokémon inside at some age, but this notion of "just let them do what they enjoy" is so contradictory to my personal experience
- hosh 2y ago
  In China and Taiwan, where many kids are pushed to study more, outside play would be a treat. Although I don’t know about video games. In the US, the complicating factor is that parents get in trouble for letting kids play unsupervised outside. Both custom and legislation discourages this kind of parenting. There is an advocacy group in the US trying to lobby for legislative protections for parents, so “just let them play outside” means something a bit different.
lambdaxyzw 2y ago
>Just let the kids play outside. I did, most of my young life, and I'm still myopic. This can't be so easy
- thsksbd 2y ago
  At what time? Where? How much? Did you play an hour a day during solar noon? (It would actually be cool to see if myopia rates change along towns near a time zone border -> kids getting out of school during the brighter time of the day)
  - hosh 2y ago
    They were comparing against kids in Australia. I forgot the exact details, but the policy developed was to add additional time during schools, and educating parents. Two hours a day cumulative, five day a week or something along those lines. This isn’t something one has to spend a lot of time optimizing within certain latitudes, since there are benefits for kids being outdoors beyond halting progression of myopia. Although, if you think this can reverse myopia, it is worth biohacking. If I recall, the article I read on this was posted on HN.
- hosh 2y ago
  It is about 20 hours of outside play a week, more or less, from early childhood, through tweens, teens, and into college. When you mean you did, most of your young life, was it about that much? The second thing I would ask is if you have astigmatism or myopia. They are not the same thing. The third thing is that the Taiwanese protocol included an early childhood intervention for a portion of the population. They have a test and an additional treatment. I don’t remember the details. If you have myopia instead of astigmatism, you might be one of those kids. Lastly, there are still some kids who develop myopia anyways in Taiwan after establishing this program.
- robwwilliams 2y ago
  Did you read recreationally as a child? I did not read books until I was 13. Not one before 12—-mild dyslexia. Emmetropic though to my 70s. My kids were both heavy readers almost as toddlers, as was my wife. All are 8 diopters myopic. Saved by dyslexia ;-)
robwwilliams 2y ago
No, myopia is definitely PARTLY heritable. Over 100 regions of the human genome are known to contribute to myopia development. Here is an excellent paper in Nature Genetics: https://www.nature.com/articles/s41588-020-0599-0 https://www.nature.com/articles/s41588-020-0599-0 But you are right that environmental factors are also critical. Most types of myopia are modulated by gene-by-environmental interactions. Lots of near-work is the number 1 culprit. But susceptibility to near work is a function of your genome.
Anotheroneagain 2y ago
It's from poorly grown orbits from lead deficiency. Genetics only determines what defect it causes.
theshackleford 2y ago
> just let the kids play outside I grew up rurally and can guarantee I spent more time outside than most. It was almost impossible to get me back inside. I’d leave early AM and go explore our until dark day after day, month after month year after year. Yet I still ended up with myopia (that started very young.) Of course, I probably just got unlucky. Across a population it’s probably good advice, but it’s not a magic bullet and it’s not a guaranteed answer. That being said if I was inside, I as almost guaranteed to have my nose in a book. Wonder if that had any impact despite my consistent exposure to outside.

by hosh 2y ago

lucb1e 2y ago

> Just let I don't know about you, but in my case that would have been "just push". RCT1+2 was a lot more fun and even if I would play with the (often mean) village kids, they too were more into video games than ball games, albeit more something like Postal (rated for mature audiences, like ten years older than we were). There was some voluntary playing outside as well as inverse curfews imposed to make sure we don't only game and watch Pokémon inside at some age, but this notion of "just let them do what they enjoy" is so contradictory to my personal experience

hosh 2y ago
In China and Taiwan, where many kids are pushed to study more, outside play would be a treat. Although I don’t know about video games. In the US, the complicating factor is that parents get in trouble for letting kids play unsupervised outside. Both custom and legislation discourages this kind of parenting. There is an advocacy group in the US trying to lobby for legislative protections for parents, so “just let them play outside” means something a bit different.

lambdaxyzw 2y ago

>Just let the kids play outside. I did, most of my young life, and I'm still myopic. This can't be so easy

thsksbd 2y ago
At what time? Where? How much? Did you play an hour a day during solar noon? (It would actually be cool to see if myopia rates change along towns near a time zone border -> kids getting out of school during the brighter time of the day)
- hosh 2y ago
  They were comparing against kids in Australia. I forgot the exact details, but the policy developed was to add additional time during schools, and educating parents. Two hours a day cumulative, five day a week or something along those lines. This isn’t something one has to spend a lot of time optimizing within certain latitudes, since there are benefits for kids being outdoors beyond halting progression of myopia. Although, if you think this can reverse myopia, it is worth biohacking. If I recall, the article I read on this was posted on HN.
hosh 2y ago
It is about 20 hours of outside play a week, more or less, from early childhood, through tweens, teens, and into college. When you mean you did, most of your young life, was it about that much? The second thing I would ask is if you have astigmatism or myopia. They are not the same thing. The third thing is that the Taiwanese protocol included an early childhood intervention for a portion of the population. They have a test and an additional treatment. I don’t remember the details. If you have myopia instead of astigmatism, you might be one of those kids. Lastly, there are still some kids who develop myopia anyways in Taiwan after establishing this program.
robwwilliams 2y ago
Did you read recreationally as a child? I did not read books until I was 13. Not one before 12—-mild dyslexia. Emmetropic though to my 70s. My kids were both heavy readers almost as toddlers, as was my wife. All are 8 diopters myopic. Saved by dyslexia ;-)

robwwilliams 2y ago

No, myopia is definitely PARTLY heritable. Over 100 regions of the human genome are known to contribute to myopia development. Here is an excellent paper in Nature Genetics: https://www.nature.com/articles/s41588-020-0599-0 https://www.nature.com/articles/s41588-020-0599-0 But you are right that environmental factors are also critical. Most types of myopia are modulated by gene-by-environmental interactions. Lots of near-work is the number 1 culprit. But susceptibility to near work is a function of your genome.

Anotheroneagain 2y ago

It's from poorly grown orbits from lead deficiency. Genetics only determines what defect it causes.

theshackleford 2y ago

> just let the kids play outside I grew up rurally and can guarantee I spent more time outside than most. It was almost impossible to get me back inside. I’d leave early AM and go explore our until dark day after day, month after month year after year. Yet I still ended up with myopia (that started very young.) Of course, I probably just got unlucky. Across a population it’s probably good advice, but it’s not a magic bullet and it’s not a guaranteed answer. That being said if I was inside, I as almost guaranteed to have my nose in a book. Wonder if that had any impact despite my consistent exposure to outside.