4 ms·
Why do they say it's "specific to each host" and not some ultra-simple algorithm like "flip the sign on $PREDATOR_FEAR_COEFFICIENT"? One might suppose that "fea
by dTal 2y ago
Why do they say it's "specific to each host" and not some ultra-simple algorithm like "flip the sign on $PREDATOR_FEAR_COEFFICIENT"? One might suppose that "fear of predators" is a highly conserved, re-used mechanism across a wide variety of organisms that specialize it to different predators as an "implementation detail", and toxoplasmosis attacks some feature common to everything rather than having a huge database of different creatures and their predators. Perhaps that is what they mean, but it's an odd way to put it.
- shagie 2y ago> The primary mechanisms of T. gondii–induced behavioral changes in rodents occur through epigenetic remodeling in neurons that govern the relevant behaviors (e.g. hypomethylation of arginine vasopressin-related genes in the medial amygdala, which greatly decrease predator aversion). And https://en.wikipedia.org/wiki/Toxoplasma_gondii#Behavioral_differences_of_infected_hosts https://en.wikipedia.org/wiki/Toxoplasma_gondii#Behavioral_d... It's got a whole list of different things that it does. Yes, some of that could be "epigenetic tweaking a gene that looks like this" would have different effects in different species (and even different genotypes - different effects for men and women). Changing the epigenetic of the regulatory genes can do different things in different species where the regulation genes have taken on different functions. Masterpiece of epigenetic engineering – how Toxoplasma gondii reprogrammes host brains to change fear to sexual attraction - https://onlinelibrary.wiley.com/doi/10.1111/mec.13006 https://onlinelibrary.wiley.com/doi/10.1111/mec.13006