4 ms·

It would be interesting to see a comparative study of glp1 agitators to intermittent fasting. It surprises me that people will spend huge amounts on a drug whic

It would be interesting to see a comparative study of glp1 agitators to intermittent fasting. It surprises me that people will spend huge amounts on a drug which makes them feel less full, rather than have the tiny amount of willpower it takes to just not eat.

hombre_fatal 2y ago
Don't be so fast to assume that your willpower isn't just from genetic luck. You might as well be surprised some people are short. I mean, look how much better your life is as someone tall. We humans are very quick to assume our positive traits and outcomes come from conscious decisions to make things that way. It's why every successful person has a book about how they chose to become successful. They just worked hard. It's something we want to believe rather than admit anything came down to luck of the draw.
- reacharavindh 2y ago
  You’re right in your argument about “just do this” suggestions without considering how hard it can be based on intrinsic factors. I feel there is a point in the thread you’re commenting on though. It would be scientifically interesting to know whether the desired(positive) outcomes of this drug can be replicated by consciously controlling the quantity or quality of food without the use of the drug(by those who can). Still, presenting the result in a useful way rather than stating the drug is useless. If you had a way to get the same results without any pharmaceutical intervention, and you’re a lucky one that _can_ do it, wouldn’t you want to know how?
  - llamaimperative 2y ago
    It has been tested, Ozempic wins. These drugs are usually tested specifically on people who have tried and failed dieting and exercise interventions. I doubt any doctor is prescribing this without first asking, “have you tried diet and exercise?” The side effects can be pretty gnarly for some people and it’s very expensive and hard to obtain.
- nate_meurer 2y ago
  And not just genetic luck, but luck of childhood circumstances. Lots of people were given a deranged relationship to food as a child by their parents, leading in many cases to actual metabolic derangement as well.
cco 2y ago
The common theme in normal weight individuals is their comparative lack of food drive, not an outsized capacity for willpower. When you talk to "skinny" people you'll hear things like they just forgot to eat or I just had a couple bites of cake then felt full/had enough. Alternatively when you speak with heavier people you'll realize that they're white knuckling their entire lives (because calories are so abundant). On average they're actually exerting more willpower around food than skinnier people. Not everyone of course, there are folks in either camp, but at population scale lack of food drive is what keeps people skinny in a calorie rich, low activity environment.
pedalpete 2y ago
I definitely could have worded this better. I'm NOT suggesting that people who struggle with weight just don't have willpower. I was suggesting that it would be interesting to see a study comparing 2 modalities.

hombre_fatal 2y ago

Don't be so fast to assume that your willpower isn't just from genetic luck. You might as well be surprised some people are short. I mean, look how much better your life is as someone tall. We humans are very quick to assume our positive traits and outcomes come from conscious decisions to make things that way. It's why every successful person has a book about how they chose to become successful. They just worked hard. It's something we want to believe rather than admit anything came down to luck of the draw.

reacharavindh 2y ago
You’re right in your argument about “just do this” suggestions without considering how hard it can be based on intrinsic factors. I feel there is a point in the thread you’re commenting on though. It would be scientifically interesting to know whether the desired(positive) outcomes of this drug can be replicated by consciously controlling the quantity or quality of food without the use of the drug(by those who can). Still, presenting the result in a useful way rather than stating the drug is useless. If you had a way to get the same results without any pharmaceutical intervention, and you’re a lucky one that _can_ do it, wouldn’t you want to know how?
- llamaimperative 2y ago
  It has been tested, Ozempic wins. These drugs are usually tested specifically on people who have tried and failed dieting and exercise interventions. I doubt any doctor is prescribing this without first asking, “have you tried diet and exercise?” The side effects can be pretty gnarly for some people and it’s very expensive and hard to obtain.
nate_meurer 2y ago
And not just genetic luck, but luck of childhood circumstances. Lots of people were given a deranged relationship to food as a child by their parents, leading in many cases to actual metabolic derangement as well.

cco 2y ago

The common theme in normal weight individuals is their comparative lack of food drive, not an outsized capacity for willpower. When you talk to "skinny" people you'll hear things like they just forgot to eat or I just had a couple bites of cake then felt full/had enough. Alternatively when you speak with heavier people you'll realize that they're white knuckling their entire lives (because calories are so abundant). On average they're actually exerting more willpower around food than skinnier people. Not everyone of course, there are folks in either camp, but at population scale lack of food drive is what keeps people skinny in a calorie rich, low activity environment.

pedalpete 2y ago

I definitely could have worded this better. I'm NOT suggesting that people who struggle with weight just don't have willpower. I was suggesting that it would be interesting to see a study comparing 2 modalities.