Overdose is less likely to happen with an unadulterated product because the dosage can actually be measured. You can't measure a dose with a product of unknown

Overdose is less likely to happen with an unadulterated product because the dosage can actually be measured. You can't measure a dose with a product of unknown concentration. The dose response curves and ED50s are known for all of these substances but people keep dying because they don't actually know how much they're taking