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There are all sorts of custom biological manufacturing companies, they are quite cheap. Like “i spent more at lunch” cheap for custom DNA sequences. When thes
by colechristensen 2y ago
There are all sorts of custom biological manufacturing companies, they are quite cheap. Like “i spent more at lunch” cheap for custom DNA sequences. When these kinds of things become routine the manufacturing cost gets very low. This particular technology may or may not still be expensive, but i doubt making it cheap will be a particularly interesting or important challenge. EDIT: maybe uninteresting and unimportant are the wrong ways to put it, it's amazing that I can get a completely custom plasmid for $30. I'm just betting the manufacturing is not going to be a major speed bump on the critical path
- giantg2 2y agoThe big thing with pricing is that this is cancer, life-or-death. The companies know they can charge almost anything if it's highly effective. I wouldn't be surprised if the pricing is 100x or even 1000x the actual manufacturing cost. I'm sure some extra money is needed for investors and R&D, but in a lot of cases the pricing seems obscene for existing products/drugs even taking those into account.
- colechristensen 2y agoThe problem is how do you price fairly when hitting on a therapy that makes it to production is like winning the lottery because it's so rare. Then you get a monopoly with a patent and start thinking about shareholders and it's not like there's any sort of valid competition in breakthrough medicine. The whole industry is screwed up.