How do you genetically engineer a resistance to fluid in the lungs, or radiation exposure, or whatever all the other interesting ways to die in space are? Imag

How do you genetically engineer a resistance to fluid in the lungs, or radiation exposure, or whatever all the other interesting ways to die in space are? Imagine all the suffering caused by failed attempts, people living their whole life with bad lungs so a privileged few can get a little closer to their space fantasy. I wouldn't want to be born into that experiment