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Nicotine is only addictive when the delivery method causes a concentration/time spike in the bloodstream. Cigarettes, vaping, and gum in particular cause large
by TimTheTinker 2y ago
Nicotine is only addictive when the delivery method causes a concentration/time spike in the bloodstream. Cigarettes, vaping, and gum in particular cause large concentration spikes, but many other delivery mechanisms do not.
I've been on nicotine patches for several years (treating ADHD - very effective) and I'm not addicted at all. I still forget and my wife often has to remind me to put on one! There are no reports to the contrary among patch users.
In fact, even moderate pipe smoking reportedly isn't addictive - although it certainly is pleasurable (partly due to the nicotine, but mostly due to other compounds in the smoke). Pipe tobacco doesn't have all the additives (and nicotine salts) that cigarettes have; moreover, unlike cigarette smoking, pipe smoking normally does not involve inhalation—all of which smoothes and limits the nicotine blood concentration/time curve significantly compared to cigarettes and vaping, thus eliminating most of the addictive potential.
More info on nicotine itself - this is essentially a very broad bibliography with some commentary mixed in: https://gwern.net/nicotine https://gwern.net/nicotine