3 ms·

I thought Splenda has almost nonexistent calorie and I am not sure what makes it different from aspartame functionally. Any reputable research on the direct dam

I thought Splenda has almost nonexistent calorie and I am not sure what makes it different from aspartame functionally. Any reputable research on the direct damages caused by Splenda?

johnfernow 2y ago
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655943/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655943/ The study above references 4 different studies that indicate that artificial sweeteners can affect glucose tolerance through changes in the microbiota composition: - https://www.nature.com/articles/nature13793 https://www.nature.com/articles/nature13793 (free PDF here: https://d1wqtxts1xzle7.cloudfront.net/44081512/Artificial_Sweeteners_Induce_Glucose_Int20160324-13721-17qzm19-libre.pdf?1458861737=&response-content-disposition=inline%3B+filename%3DArtificial_sweeteners_induce_glucose_int.pdf&Expires=1714945691&Signature=Wip368ftBoWnuP1jKqZo3vZZhfKbN-J7TWaHUCOy2kbMlOLT31MNRj3C9doX4zFC5Xj7viQeGHSgfW1x2hrsHdf7m~E3Stw-nN4pqeGzVT~zLS67EWS0RgOgEV1PX7-cGsLhjbw3mT4HaA7C2yrKLcX0~lOrVShgV5qvq4YKDLwybJXKIQ8EFwlxOjpcKDdGub6q2Udg2fcAm3dls0v6d0N0xytdY~KE0uql06uuQg2XtwfFBJ4e0daNtTyCGV-UoKQvxMn4MeJBljdmz4YnO8uQSd5-IRDDIYNs3y5CC~64tfPupmJRdjNQtmpRPjxZCN7SjKQ3TsV2lZzD9D57Pg__&Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA https://d1wqtxts1xzle7.cloudfront.net/44081512/Artificial_Sw... ) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363527/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363527/ - https://www.cell.com/cell/fulltext/S0092-8674(22)00919-9 https://www.cell.com/cell/fulltext/S0092-8674(22)00919-9 - https://www.cell.com/cell/fulltext/S0092-8674(22)00994-1 https://www.cell.com/cell/fulltext/S0092-8674(22)00994-1 The article also references 4 studies that indicate that artificial sweeteners have side effects in terms of obesity, cardiovascular disease, and mortality. - https://www.bmj.com/content/378/bmj-2022-071204 https://www.bmj.com/content/378/bmj-2022-071204 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538252/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538252/ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506029/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506029/ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946744/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946744/
- gloryjulio 2y ago
  What about dosage? I couldn't find a succinct summary. Can you point out the part indicating how much they experimented with? How many grams of Splendar per day would indicate danger?

I thought Splenda has almost nonexistent calorie and I am not sure what makes it different from aspartame functionally. Any reputable research on the direct damages caused by Splenda?

johnfernow 2y ago

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655943/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655943/ The study above references 4 different studies that indicate that artificial sweeteners can affect glucose tolerance through changes in the microbiota composition: - https://www.nature.com/articles/nature13793 https://www.nature.com/articles/nature13793 (free PDF here: https://d1wqtxts1xzle7.cloudfront.net/44081512/Artificial_Sweeteners_Induce_Glucose_Int20160324-13721-17qzm19-libre.pdf?1458861737=&response-content-disposition=inline%3B+filename%3DArtificial_sweeteners_induce_glucose_int.pdf&Expires=1714945691&Signature=Wip368ftBoWnuP1jKqZo3vZZhfKbN-J7TWaHUCOy2kbMlOLT31MNRj3C9doX4zFC5Xj7viQeGHSgfW1x2hrsHdf7m~E3Stw-nN4pqeGzVT~zLS67EWS0RgOgEV1PX7-cGsLhjbw3mT4HaA7C2yrKLcX0~lOrVShgV5qvq4YKDLwybJXKIQ8EFwlxOjpcKDdGub6q2Udg2fcAm3dls0v6d0N0xytdY~KE0uql06uuQg2XtwfFBJ4e0daNtTyCGV-UoKQvxMn4MeJBljdmz4YnO8uQSd5-IRDDIYNs3y5CC~64tfPupmJRdjNQtmpRPjxZCN7SjKQ3TsV2lZzD9D57Pg__&Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA https://d1wqtxts1xzle7.cloudfront.net/44081512/Artificial_Sw... ) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363527/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363527/ - https://www.cell.com/cell/fulltext/S0092-8674(22)00919-9 https://www.cell.com/cell/fulltext/S0092-8674(22)00919-9 - https://www.cell.com/cell/fulltext/S0092-8674(22)00994-1 https://www.cell.com/cell/fulltext/S0092-8674(22)00994-1 The article also references 4 studies that indicate that artificial sweeteners have side effects in terms of obesity, cardiovascular disease, and mortality. - https://www.bmj.com/content/378/bmj-2022-071204 https://www.bmj.com/content/378/bmj-2022-071204 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538252/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538252/ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506029/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506029/ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946744/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946744/

gloryjulio 2y ago
What about dosage? I couldn't find a succinct summary. Can you point out the part indicating how much they experimented with? How many grams of Splendar per day would indicate danger?