For people who misinterpreted the title like me, thinking that exercising is negative: Conclusion Our findings showed that high CRF is strongly associated wit

For people who misinterpreted the title like me, thinking that exercising is negative: Conclusion Our findings showed that high CRF is strongly associated with lower risk of premature mortality, incident chronic conditions (ie, hypertension, heart failure, stroke, atrial fibrillation, dementia and depression), and poor prognosis in those with existing chronic conditions. The consistency of the evidence across a variety of health outcomes demonstrates the importance of CRF and the need to incorporate this measure in routine clinical and public health practice. Future studies should focus on outcomes with limited evidence and where the certainty of the evidence was rated as very low by improving study quality.