3 ms·
It’s been in use for 20 years or so, so I expect we’ve discovered most long term effects.
by prepend 2y ago
It’s been in use for 20 years or so, so I expect we’ve discovered most long term effects.
- toast0 2y agoWikipedia said semaglutide was approved by the FDA in 2017. With later approvals in the EU, Japan and Australia. Was it approved earlier elsewhere? Use for weight loss is relatively new as well. Approvals for that use are more recent, but off label use preceeds approval.
- ceejayoz 2y agoFirst of the GLP-1 receptor agonists was https://en.wikipedia.org/wiki/Exenatide https://en.wikipedia.org/wiki/Exenatide in 2005 (with clinical trials prior to that). Safety profile is reasonably well understood with two decades under our belts.
- addicted 2y agoWasn’t it approved for people with diabetes? I’m assuming the tests were done on people with diabetes then. Were there tests done on non diabetic people as well?