I think we have enough real world case studies now with previously stubborn fatties whom (allegedly) tried everything but finally lost weight on ozempic due to

I think we have enough real world case studies now with previously stubborn fatties whom (allegedly) tried everything but finally lost weight on ozempic due to appetite suppression. 6 hours of running is 4000-8000 calories / 1-2lb week depending on body size. That's your basic 1-2% of BW deficit for weight loss. Except it's a much harder behaviour change to adopt.