3 ms·
A couple of caveats about the article: First, there were only two cases. Second, the article notes: "Based on non-human primate and mouse models, cross-species
by bikenaga 3y ago
A couple of caveats about the article: First, there were only two cases. Second, the article notes: "Based on non-human primate and mouse models, cross-species transmission of CJD is plausible. Due to the challenge of distinguishing sCJDMM1 from CWD without detailed prion protein characterization, it is not possible to definitively rule out CWD in these cases." I'm not a biologist, so if someone knows more please correct me, but I read this to mean that they definitely found CJD in the patients but could not establish the presence of the CWD prion. So they say "is plausible" and "not possible to definitely rule out".
In PA, CWD has been detected in a lot of areas (https://pagame.maps.arcgis.com/apps/dashboards/b3c0fd44cc5944ebbc2229ede897b2ae https://pagame.maps.arcgis.com/apps/dashboards/b3c0fd44cc594...) but the prevalence seems low: The dashboard is showing 102,933 CWD samples with 1857 cases of CWD detected. (It's not clear how representative this is, or how the samples were acquired.)
- nightowl_games 3y ago"only two cases" from the same hunters lodge is significant enough to warrant suspicion inuo the deer/human prion pathway. Two cases in the same location like that is actually significant. One case matters. Two really matter. Three and it's pretty serious.