Even for perpetual license games, if the game has paid DLC the developers often see mods and cheatengine as a threat to their revenues. Capcom is on the record

Even for perpetual license games, if the game has paid DLC the developers often see mods and cheatengine as a threat to their revenues. Capcom is on the record that this is part of why they put DRM and anticheat into their single-player games now, because otherwise you can get items and cosmetics with cheatengine instead of buying them off Steam/PSN/XBL