Drug combinations is the future, because of how cancers survives through mutations. All oncologists are aware of this, but the FDA is not open to it, and most o

Drug combinations is the future, because of how cancers survives through mutations. All oncologists are aware of this, but the FDA is not open to it, and most oncologists obey the FDA. Pembro, metformin, and others, once found reasonably safe in a patient, should be used in combination with chemo, pathway inhibitors. Immunology is different and I can see these working against each other, so caution is warranted there.