I don't have a Mac, but there's a lot of keys I never use. I pretty much never use function keys for anything but setting volume and brightness, I fairly rarel

I don't have a Mac, but there's a lot of keys I never use. I pretty much never use function keys for anything but setting volume and brightness, I fairly rarely use alt, escape isn't that common. I use the arrow keys just enough that I'd be annoyed without them but definitely not all the time. I could probably be fine with just ctrl, shift, enter, and the printing chars, with several weeks of work to learn some alternative to pgup/down/end/home, but I really like having those as single keys.