5 ms·

I'm genuinely curious about what mechanism would make this possible.

yieldcrv 2y ago
what I find the most humorous from people that base their whole identity around a problem with mRNA vaccines is that everything they identify as a problem is caused by a natural covid infection too and in vast greater quantities and severity, and they amusingly don’t seem to know that
- decremental 2y ago
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logicchains 2y ago
They were presumably referring to https://pubmed.ncbi.nlm.nih.gov/36548397/ https://pubmed.ncbi.nlm.nih.gov/36548397/ , where repeated vaccination with the mRNA vaccines was associated with antibody class switching towards IgG4 "tolerance" antibodies. In theory, this class switching could allow the spike proteins from the virus to persist longer in the body, causing more damage. The same phenomenon wasn't observed with non-mrna vaccines or covid infection, which has been hypothesized to be because they don't make the body's own cells produce the spike protein, so don't invoke that same immune tolerance mechanism.
zer00eyz 2y ago
To bring in some actual research: https://www.cureus.com/articles/196275-increased-age-adjusted-cancer#!/ https://www.cureus.com/articles/196275-increased-age-adjuste... A study of more than 50,000 employees at a medical institution in the United States observed the incidence of the Omicron variant epidemic based on the number of vaccine doses received (0, 1, 2, 3, and 4 or more doses) over a period of 26 weeks and showed that the number of vaccines received was positively correlated with the cumulative incidence rate of COVID-19 [46]. Susceptibility to COVID-19 infection after multiple vaccinations may be enhanced by antibody-dependent enhancement [47], immune imprinting [39,48], and immunosuppression [25-27]. This can result in a risk of exposure to viral S-protein in addition to vaccine S-protein for the multiple-vaccinated. That whole paper is... interesting. I will be curios to see if any one else finds corroborating data or if it gets toss to the side and forgotten.

what I find the most humorous from people that base their whole identity around a problem with mRNA vaccines is that everything they identify as a problem is caused by a natural covid infection too and in vast greater quantities and severity, and they amusingly don’t seem to know that

decremental 2y ago
[dead]

logicchains 2y ago

They were presumably referring to https://pubmed.ncbi.nlm.nih.gov/36548397/ https://pubmed.ncbi.nlm.nih.gov/36548397/ , where repeated vaccination with the mRNA vaccines was associated with antibody class switching towards IgG4 "tolerance" antibodies. In theory, this class switching could allow the spike proteins from the virus to persist longer in the body, causing more damage. The same phenomenon wasn't observed with non-mrna vaccines or covid infection, which has been hypothesized to be because they don't make the body's own cells produce the spike protein, so don't invoke that same immune tolerance mechanism.

zer00eyz 2y ago

To bring in some actual research: https://www.cureus.com/articles/196275-increased-age-adjusted-cancer#!/ https://www.cureus.com/articles/196275-increased-age-adjuste... A study of more than 50,000 employees at a medical institution in the United States observed the incidence of the Omicron variant epidemic based on the number of vaccine doses received (0, 1, 2, 3, and 4 or more doses) over a period of 26 weeks and showed that the number of vaccines received was positively correlated with the cumulative incidence rate of COVID-19 [46]. Susceptibility to COVID-19 infection after multiple vaccinations may be enhanced by antibody-dependent enhancement [47], immune imprinting [39,48], and immunosuppression [25-27]. This can result in a risk of exposure to viral S-protein in addition to vaccine S-protein for the multiple-vaccinated. That whole paper is... interesting. I will be curios to see if any one else finds corroborating data or if it gets toss to the side and forgotten.