First thing you can do is to 1. Contact few bioinformatics professor/researcher from your university (If your university has a bioinformatics dept) or other un

First thing you can do is to 1. Contact few bioinformatics professor/researcher from your university (If your university has a bioinformatics dept) or other universities and ask what are the problems nagging them for a long time. You will have an idea. You can also contact industries (23andme). For more info go to http://bionet.awardspace.info/company.html http://bionet.awardspace.info/company.html and see what bioinformatics companies do and what interests you. 2. In healthcare it is just an open field. You can take open data from data.gov and analyze and if you can develop an algorithm which can predict the likelihood of hospitalization post surgery in a patient then insurance companies will be drooling over that.