That's not an good tactic for a number of reasons. The attack involved a lot of drones. Hundreds. Dealing with hundreds of drones with manned fighter aircraf

That's not an good tactic for a number of reasons. The attack involved a lot of drones. Hundreds. Dealing with hundreds of drones with manned fighter aircraft is dubious and possibly a terrible mistake: committing and exposing high value assets for what is, militarily, scutwork. Fighters don't carry enough gun ammo for the purpose, because ammo is heavy and the guns fire it very rapidly: typically there is only a few seconds of gun ammo capacity in a fighter. Air to air missiles are too precious to use on these targets: they're needed to defend against high value threats and can't be wasted on these crummy, militarized model aircraft from Iran. Also, these drones fly at relatively low altitude, so defending fighters must operate at low altitude and low speed over foreign territory, which is problematic for many reasons. Finally, the drones aren't easy to find because they aren't great radar targets, being small, low altitude, and mostly made of lightweight composites: it is unlikely they can all be detected and engaged quickly enough. For all of these reasons and others, manned aircraft are poor counter for this sort of attack. Despite this fighter aircraft were used. It was reported that the US, the RAF and the IAF all used manned aircraft to bring down some of these drones. But as you know, many still reached Israel. There, cost effective ground defense did most of the work.