I patched python-mode to do this (also did something similar for node and a few other interpreters). Main thing is to add a "py-execute-line" routine and a few

I patched python-mode to do this (also did something similar for node and a few other interpreters). Main thing is to add a "py-execute-line" routine and a few others as wrappers around the file execution code. If there's interest, might post as open source. EDIT: here is a snippet (defun py-execute-line (&optional async) "Send the current line to the inferior python process using py-execute-region." (interactive "P") (save-excursion (end-of-line) (let ((end (point))) (beginning-of-line) (py-execute-region (point) end async))) ) That's the py-execute-line function, which is sending code to py-execute-region defined in python-mode (http://bazaar.launchpad.net/~python-mode-devs/python-mode/python-mode/view/head:/python-mode.el#L7828 http://bazaar.launchpad.net/~python-mode-devs/python-mode/py...). For some reason the default python mode in emacs is python.el rather than python-mode.el. So you probably want to start by using python-mode.