You can read about how it doesn't (can't)? https://blog.invisiblethings.org/2015/10/27/x86_harmful.html https://blog.invisiblethings.org/2015/10/27/x86_harmful.

You can read about how it doesn't (can't)? https://blog.invisiblethings.org/2015/10/27/x86_harmful.html https://blog.invisiblethings.org/2015/10/27/x86_harmful.html But their recommended hardware makes it pretty clear Qubes should preferably be run on open firmware and with ME as broken as reasonably possible (as has already been pointed out in the discussion here).