4 ms·

I think it's likely that the WHO is considering people like me in their recommendation. I have friends who can drink a beer, maybe two, and be quite happy and

by caeril 3y ago

I think it's likely that the WHO is considering people like me in their recommendation. I have friends who can drink a beer, maybe two, and be quite happy and satisfied. This is a phenomenon I have never been able to understand, because even a small amount of alcohol switches my reward system to REQUIRE more. If I have zero alcohol, I'm fine. But if I have one beer, I WILL have 7 more. For some portion of the human population (I've seen estimates at 15-20%), the concept of moderation is impossible - and for us, zero is the correct amount. If the WHO said "drink moderately if you don't experience dopaminergic response to ethanol, but drink zero if you do", it would be more nuanced and accurate, but public health organizations need to target their recommendations to the LCD, as simply as possible. It's the same as dietary cholesterol and salt. No health organization is going to say "run a double-blind study on yourself to find out if you are part of the population for whom dietary cholesterol impacts serum cholesterol, or sodium intake affects blood pressure, then consult this chart to see what our recommendation is for you" Instead they'll just say GROG SAY SALT AND EGGS BAD, NO EAT.

toomuchtodo 3y ago
I have a hunch if you tried a GLP-1 agonist, this reward center would evaporate. https://www.nature.com/articles/s41598-023-48267-2 https://www.nature.com/articles/s41598-023-48267-2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820218/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820218/
- caeril 3y ago
  Yes, I've seen this, but I am a bit of a fitness enthusiast, and nobody's going to prescribe semaglutide or tirzepatide until I gain 200lbs and wreck my health, which I am unwilling to do. I'm not sure if you're tried visiting a doctor lately with your own research, but they look down your nose at you if you try to advocate for your particular edge case, with pubmed articles in hand - because they are better than you, as a filthy plebian patient. These are the people who murder a quarter million Americans annually due to preventable medical errors. Why anybody with an IQ over 90 would ever bother doing business with them is beyond me. At this point, I'm just waiting for the more reputable darkweb market suppliers to catch up. But yes, you're right, I'm looking forward to trying this approach, but I refuse to grant moral sanction or financial resources to the Gatekeeper class who demand we beg Daddy's permission to make decisions about our own bodies. They are all evil, full stop.
  - deleted 3y ago
    [deleted]
  - toomuchtodo 3y ago
    All fair points.
coremoff 3y ago
I'm similar to you there; the old addage "one is too many, two is too few" (or whatever the current version of that is) always ruled my drinking; I didn't need alcohol, but when I started I'd keep going - nice to have a name for it. Unrelated to any of this, I have a number of mental health issues, and recently I found that alcohol no longer gives me any of the euphoria effects that is used to do (obviously I still had the negative effects); once I noticed that, my desire for alchol went to zero and I've not touched it since - no idea if I am still have the same response to alcohol, but I'm not going to test it, for obvious reasons :)

by caeril 3y ago

toomuchtodo 3y ago

I have a hunch if you tried a GLP-1 agonist, this reward center would evaporate. https://www.nature.com/articles/s41598-023-48267-2 https://www.nature.com/articles/s41598-023-48267-2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820218/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820218/

caeril 3y ago
Yes, I've seen this, but I am a bit of a fitness enthusiast, and nobody's going to prescribe semaglutide or tirzepatide until I gain 200lbs and wreck my health, which I am unwilling to do. I'm not sure if you're tried visiting a doctor lately with your own research, but they look down your nose at you if you try to advocate for your particular edge case, with pubmed articles in hand - because they are better than you, as a filthy plebian patient. These are the people who murder a quarter million Americans annually due to preventable medical errors. Why anybody with an IQ over 90 would ever bother doing business with them is beyond me. At this point, I'm just waiting for the more reputable darkweb market suppliers to catch up. But yes, you're right, I'm looking forward to trying this approach, but I refuse to grant moral sanction or financial resources to the Gatekeeper class who demand we beg Daddy's permission to make decisions about our own bodies. They are all evil, full stop.
- deleted 3y ago
  [deleted]
- toomuchtodo 3y ago
  All fair points.

coremoff 3y ago

I'm similar to you there; the old addage "one is too many, two is too few" (or whatever the current version of that is) always ruled my drinking; I didn't need alcohol, but when I started I'd keep going - nice to have a name for it. Unrelated to any of this, I have a number of mental health issues, and recently I found that alcohol no longer gives me any of the euphoria effects that is used to do (obviously I still had the negative effects); once I noticed that, my desire for alchol went to zero and I've not touched it since - no idea if I am still have the same response to alcohol, but I'm not going to test it, for obvious reasons :)