> We have previously shown that surgery alone, or 3-days of HFD can each evoke sufficient neuroinflammation to cause memory deficits in aged, but not young rats

> We have previously shown that surgery alone, or 3-days of HFD can each evoke sufficient neuroinflammation to cause memory deficits in aged, but not young rats. The surgery + transition onto HFD seem to be more damaging than either one alone, which makes sense that doing two harmful things is worse than doing one harmful thing.