Setting SQLite PRAGMAs via Django settings was recently merged. I would expect to see this show up in the next version or two of Django. https://code.djangopro

Setting SQLite PRAGMAs via Django settings was recently merged. I would expect to see this show up in the next version or two of Django. https://code.djangoproject.com/ticket/24018 https://code.djangoproject.com/ticket/24018 With the proper PRAGMAs set and modern hardware, you can do 400+ writes/sec with 4 uvicorn workers and ~100 clients connected. The achilles heal is writing lots of large files. That will cause concurrent requests to wait around for the disk to finish writing to the WAL.