3 ms·

It feels like science is progressing in all aspects except spinal disc replacement/regeneration.

NLPaep 3y ago
https://www.healio.com/news/orthopedics/20230209/discgenics-receives-fda-designation-for-injectable-disc-cell-therapy-treatment https://www.healio.com/news/orthopedics/20230209/discgenics-...
- harikb 3y ago
  Looking forward to this. My guess though will be that only methods that require a "subscription" will see the light of day. As in, things that require repeated applications, life long medication etc.
- deelowe 3y ago
  Unfortunately, repeated injections cause scar tissue build up. This is the main reason I've steered clear of any injection based therapy. They work fine at first but over time accelerate degeneration.
okdood64 3y ago
Hair loss science sure isn’t.
- adrianN 3y ago
  I’m under the impression that there are multiple effective treatments for hair loss
  - eropple 3y ago
    Yeah, some of them work, at least for some people. Almost every male in my family, and all the direct-line male relatives on both sides, went bald by their late twenties. Maybe I just got some good dice rolls and so this is a tiger rock, but when I noticed my hair just beginning to thin around age 23 I got on finasteride and have been taking it ever since. I'm 36 now, full head of hair, and if anything my hair grows fast enough that it's kind of annoying how often I need a trim.
  - olejorgenb 3y ago
    With problematic/risky side effects though? (https://en.wikipedia.org/wiki/Finasteride#Finasteride_for_androgenetic_alopecia_(hair_loss_in_men) https://en.wikipedia.org/wiki/Finasteride#Finasteride_for_an...)
    - eropple 3y ago
      Meta-studies seem to indicate that the preponderance of the evidence is against, not for, scary side effects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481923/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481923/
huytersd 3y ago
Not far enough with HIV. Yes we have pills that significantly expand lifespan (by up to 30-40 years), but they make you severely prone to cancer and your immune system never really has a full chance to recover making you prone to all kinds of opportunistic infections. We really need a cure and I don’t think we’re moving fast enough with CRISPR based solutions. We know how to excise the HIV, we know how to add the CCR5 gene to T cells. We need to move faster.

https://www.healio.com/news/orthopedics/20230209/discgenics-receives-fda-designation-for-injectable-disc-cell-therapy-treatment https://www.healio.com/news/orthopedics/20230209/discgenics-...

harikb 3y ago
Looking forward to this. My guess though will be that only methods that require a "subscription" will see the light of day. As in, things that require repeated applications, life long medication etc.
deelowe 3y ago
Unfortunately, repeated injections cause scar tissue build up. This is the main reason I've steered clear of any injection based therapy. They work fine at first but over time accelerate degeneration.

okdood64 3y ago

Hair loss science sure isn’t.

adrianN 3y ago
I’m under the impression that there are multiple effective treatments for hair loss
- eropple 3y ago
  Yeah, some of them work, at least for some people. Almost every male in my family, and all the direct-line male relatives on both sides, went bald by their late twenties. Maybe I just got some good dice rolls and so this is a tiger rock, but when I noticed my hair just beginning to thin around age 23 I got on finasteride and have been taking it ever since. I'm 36 now, full head of hair, and if anything my hair grows fast enough that it's kind of annoying how often I need a trim.
- olejorgenb 3y ago
  With problematic/risky side effects though? (https://en.wikipedia.org/wiki/Finasteride#Finasteride_for_androgenetic_alopecia_(hair_loss_in_men) https://en.wikipedia.org/wiki/Finasteride#Finasteride_for_an...)
  - eropple 3y ago
    Meta-studies seem to indicate that the preponderance of the evidence is against, not for, scary side effects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481923/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481923/

huytersd 3y ago

Not far enough with HIV. Yes we have pills that significantly expand lifespan (by up to 30-40 years), but they make you severely prone to cancer and your immune system never really has a full chance to recover making you prone to all kinds of opportunistic infections. We really need a cure and I don’t think we’re moving fast enough with CRISPR based solutions. We know how to excise the HIV, we know how to add the CCR5 gene to T cells. We need to move faster.