It depends on how the search is implemented exactly and what the context is, but assuming I've searched for "cono", I would expect results that directly match "

It depends on how the search is implemented exactly and what the context is, but assuming I've searched for "cono", I would expect results that directly match "cono" to come first, then results that also match "coño". Similarly to how I'd expect to still get reasonable results if I type "beleive" instead of "believe". That said, this is obviously pretty context-dependent, in some settings it will make more sense to do an exact-match search, in which case you'd want to differentiate n and ñ (while still handling different possible unicode variants of ñ if those exist).