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"Estrogen a more powerful breast cancer culprit than we realized" https://news.harvard.edu/gazette/story/2023/05/estrogen-a-more-powerful-breast-cancer-culprit

• wizzwizz4 3y ago
  This article buries the lede, but boy is that lede fascinating. > Estrogen receptors are known to bind to certain regions of the genome when a cell is stimulated by estrogen. The researchers found that these estrogen-binding sites were frequently next to the zones where the early DNA breaks took place. Estrogens are important for other things, so (what's effectively) menopause would be a rather impractical preventative measure for most people – but knowledge is still power. I'll have to read the paper sometime. https://doi.org/10.1038/s41586-023-06057-w https://doi.org/10.1038/s41586-023-06057-w