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Is there a chance that, like DNA origami, this technology might face challenges in finding real-world (or even basic science) applications? While it appears int

Is there a chance that, like DNA origami, this technology might face challenges in finding real-world (or even basic science) applications? While it appears intriguing, is there potential for these structures to be effectively used in drug delivery or enabling reactions or processes that would otherwise be unfeasible? ASK HN: Can you list a few non-obvious uses for microscale 3D structures?

tdudhhu 3y ago
Maybe for some types of osmosis? Creating tiny holes for osmosis is of course already possible but with 3D structures it might be possible to create things like ventury effects.
logtempo 3y ago
> For their part, the researchers have already experimented with producing both hard and soft particles, made of ceramics and of hydrogels. The first could see applications in microelectronics manufacturing and the latter in drug delivery in the body. “There’s a wide array of applications, and we’re just beginning to explore them,” said Maria Dulay, senior research scientist in the DeSimone lab and co-author of the paper. Traduction of the last sentence: either mean "we don't know the applications it can have" or it's honest and there is many applications coming soon that can't be discussed publicly for some industrial reason.
nuc1e0n 3y ago
Could you make a surface with an embedded array of tiny tesla valves with this technology?
- gtsnexp 3y ago
  Tiny tesla valves would be super interesting, potentially in the context of cell sorting, perhaps?
- samstave 3y ago
  https://hackaday.com/2021/06/20/tiny-tesla-valves-etched-in-glass/ https://hackaday.com/2021/06/20/tiny-tesla-valves-etched-in-... Seems like it would work beautifully. What would be cool is to make a logic-gate-tesla-valve-micro-hydraulic computer? -- The video on micro etching glass with HF is highly informative on this post... he talks about etching tesla valves at the end... https://i.imgur.com/dADV2q4.jpg https://i.imgur.com/dADV2q4.jpg <-- 30 microns long with channel width of 4 microns via etched glass... https://i.imgur.com/pJsiuCg.png https://i.imgur.com/pJsiuCg.png https://youtu.be/gQnmP7UD_zk?t=806 https://youtu.be/gQnmP7UD_zk?t=806 -- So I wonder what resolution would be possible via the 3d version. What would be really interesting to see with this method would be to make a blend of a spiral-screw with the tesla valves to climb or control vertical rates of flow. --- Since this process can print in ceramics, I wonder if the can effectively make a "super-conductive-nano-wire with spiraling interconnected bucky-ball-shaped lattice of particles"
  - nuc1e0n 3y ago
    Yeah those ones are etched to be parallel to the surface. I was thinking of tiny circularly rotated (lathed?) ones oriented to the normal of the surface. So sticking straight through it. Then you could have a surface that substances can permeate through, but only in one direction. So kinda like a 3d printed Maxwell's demon. https://youtu.be/11QkX4u6RJg https://youtu.be/11QkX4u6RJg
    - samstave 3y ago
      Yeah, I was expressing the same thought... Cool that we see things and just go "huh, wouldnt it be cool if" and we can easily visualize something once we are given a small amount of Starter Dough for our Food For Thought. I was really interested in this spiral Wirtz Pump https://www.youtube.com/watch?v=wCxRHueX6jQ https://www.youtube.com/watch?v=wCxRHueX6jQ So if one were to combine a wirtz pump with a tesla valve, you might be able to eliminate the the air gaps in the tube. One thing would be cool too - is that you could easily use the tesla valves to merge fluids wihtout risking back-mixing ocurring at the confluence point - and you could direct fluids from any direction without fearing gravity fucking with your flow (tesla-valve-pipes may be really useful in weightless space? I wonder if you could print flexible materials with this 3D printing method, and you could make a spiraling tesla-valve small tubing. if you have micro versions, you could use the confuence points to mix proteins/amino-acids to stemcells in very precise amounts to determine which affect a certain expression from the stem cells. (there was a researcher at UCSF who was doing this - sans tesla valves... and that was 10+ years ago...)

tdudhhu 3y ago

Maybe for some types of osmosis? Creating tiny holes for osmosis is of course already possible but with 3D structures it might be possible to create things like ventury effects.

logtempo 3y ago

> For their part, the researchers have already experimented with producing both hard and soft particles, made of ceramics and of hydrogels. The first could see applications in microelectronics manufacturing and the latter in drug delivery in the body. “There’s a wide array of applications, and we’re just beginning to explore them,” said Maria Dulay, senior research scientist in the DeSimone lab and co-author of the paper. Traduction of the last sentence: either mean "we don't know the applications it can have" or it's honest and there is many applications coming soon that can't be discussed publicly for some industrial reason.

nuc1e0n 3y ago

Could you make a surface with an embedded array of tiny tesla valves with this technology?

gtsnexp 3y ago
Tiny tesla valves would be super interesting, potentially in the context of cell sorting, perhaps?
samstave 3y ago
https://hackaday.com/2021/06/20/tiny-tesla-valves-etched-in-glass/ https://hackaday.com/2021/06/20/tiny-tesla-valves-etched-in-... Seems like it would work beautifully. What would be cool is to make a logic-gate-tesla-valve-micro-hydraulic computer? -- The video on micro etching glass with HF is highly informative on this post... he talks about etching tesla valves at the end... https://i.imgur.com/dADV2q4.jpg https://i.imgur.com/dADV2q4.jpg <-- 30 microns long with channel width of 4 microns via etched glass... https://i.imgur.com/pJsiuCg.png https://i.imgur.com/pJsiuCg.png https://youtu.be/gQnmP7UD_zk?t=806 https://youtu.be/gQnmP7UD_zk?t=806 -- So I wonder what resolution would be possible via the 3d version. What would be really interesting to see with this method would be to make a blend of a spiral-screw with the tesla valves to climb or control vertical rates of flow. --- Since this process can print in ceramics, I wonder if the can effectively make a "super-conductive-nano-wire with spiraling interconnected bucky-ball-shaped lattice of particles"
- nuc1e0n 3y ago
  Yeah those ones are etched to be parallel to the surface. I was thinking of tiny circularly rotated (lathed?) ones oriented to the normal of the surface. So sticking straight through it. Then you could have a surface that substances can permeate through, but only in one direction. So kinda like a 3d printed Maxwell's demon. https://youtu.be/11QkX4u6RJg https://youtu.be/11QkX4u6RJg
  - samstave 3y ago
    Yeah, I was expressing the same thought... Cool that we see things and just go "huh, wouldnt it be cool if" and we can easily visualize something once we are given a small amount of Starter Dough for our Food For Thought. I was really interested in this spiral Wirtz Pump https://www.youtube.com/watch?v=wCxRHueX6jQ https://www.youtube.com/watch?v=wCxRHueX6jQ So if one were to combine a wirtz pump with a tesla valve, you might be able to eliminate the the air gaps in the tube. One thing would be cool too - is that you could easily use the tesla valves to merge fluids wihtout risking back-mixing ocurring at the confluence point - and you could direct fluids from any direction without fearing gravity fucking with your flow (tesla-valve-pipes may be really useful in weightless space? I wonder if you could print flexible materials with this 3D printing method, and you could make a spiraling tesla-valve small tubing. if you have micro versions, you could use the confuence points to mix proteins/amino-acids to stemcells in very precise amounts to determine which affect a certain expression from the stem cells. (there was a researcher at UCSF who was doing this - sans tesla valves... and that was 10+ years ago...)