4 ms·
That the F.nucleatum bacterium is associated with colon cancer has been known for some time, e.g.: https://pubmed.ncbi.nlm.nih.gov/27876571/ https://pubmed.ncb
by A_D_E_P_T 3y ago
That the F.nucleatum bacterium is associated with colon cancer has been known for some time, e.g.: https://pubmed.ncbi.nlm.nih.gov/27876571/ https://pubmed.ncbi.nlm.nih.gov/27876571/
It is also associated with "poor rates of both overall survival and progression-free survival" in cervical cancer: https://pubmed.ncbi.nlm.nih.gov/33197886/ https://pubmed.ncbi.nlm.nih.gov/33197886/
And it is "associated with shorter survival" when found in esophageal cancer:
https://pubmed.ncbi.nlm.nih.gov/27769987/ https://pubmed.ncbi.nlm.nih.gov/27769987/
It is also linked to gastric cancer: https://www.nature.com/articles/s41598-017-18596-0 https://www.nature.com/articles/s41598-017-18596-0
All in all, it's obviously a pretty nasty little customer. It might be worth screening for it, and attempting to eliminate it if possible.
- toomuchtodo 3y agoVaccine candidate?
- j-bos 3y agoThere's a benign bacteria being sold to outcompete it.
- NegativeLatency 3y agoWhat's that?
- isk517 3y agohttps://news.ycombinator.com/item?id=37634713 https://news.ycombinator.com/item?id=37634713
- friend_and_foe 3y agoThat's a different species of bacteria altogether.
- jerrysievert 3y ago> That's a different species of bacteria altogether. likely hence the "out-compete", by a different species
- friend_and_foe 3y agoThe bacteria in the link is Streptococcus mutans, the species in this article is Fusobacterium nucleatum. They're not the same species, one can't be used to replace the other.
- xk_id 3y agoIt can be, if they secrete inhibitory metabolites and/or compete for the same feeding substrates.
- hereme888 3y agoA $20k probiotic vs a $20 round of antibiotics?
- j-bos 3y agoIn theory, a cure vs a paliative.
- kilotaras 3y ago> Oh, for the ship-to-your-house version in May, we're dropping the price to $250 https://twitter.com/LanternBioworks/status/1769929390404899102 https://twitter.com/LanternBioworks/status/17699293904048991...
- hereme888 3y agoWell, at that price I might be interested.
- A_D_E_P_T 3y agoYes, that seems to be the case, at least in principle: https://pubmed.ncbi.nlm.nih.gov/36634619/ https://pubmed.ncbi.nlm.nih.gov/36634619/ I'm not aware of any actual projects in development, but it could certainly be that some are in their very early stages.