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Well you can’t use it as a vaccine since there would be no hiv to preemptively excise.
by huytersd 3y ago
Well you can’t use it as a vaccine since there would be no hiv to preemptively excise.
- 1letterunixname 3y agoWhat we need is a reliable CRISPR vaccine that confers the CCR5 SNP and essentially give it to everyone.
- huytersd 3y agoYeah, we don’t even need to get every cell at that point, just a sizable number of the CD4 cells that are relatively easily accessible. The HIV would destroy every CD4 that isn’t CCR5 by itself. The antibodies would clean up the rest of the virons. Theoretically that would work as a cure too if you could excise the hiv and insert the CCR5 widely enough.