Yes, pretty close so full translation is easy if you have the source code. If not, emulation is the normal way. My emulator was faster than native 8080 code on

Yes, pretty close so full translation is easy if you have the source code. If not, emulation is the normal way. My emulator was faster than native 8080 code on everything but vanilla 8088 PCs, so it's more than sufficient. I address translation in depth in my Retro Sargon project, an exercise in getting a vintage Z80 (8080 superset) assembly language program working on modern PCs. https://github.com/billforsternz/retro-sargon https://github.com/billforsternz/retro-sargon See the "Yet More Details" section in the README.