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Leaky blood brain barrier does not bode well for the future, especially with mass and repeated infections. This is associated with Alzheimer’s, dementia, and ot

Leaky blood brain barrier does not bode well for the future, especially with mass and repeated infections. This is associated with Alzheimer’s, dementia, and other neurodegenerstive disorders: https://www.nature.com/articles/nrneurol.2017.188 https://www.nature.com/articles/nrneurol.2017.188

formvoltron 3y ago
Wow that's terrible. Well.. science has major incentive to find cures now. How many have long covid? Or maybe even subclinical long covid that may silently boost Alzheimer's risk? On a more positive note, they recently found that there is some sort of frequency that may enhance / trigger the natural junk clearance mechanisms that go on during sleep.
- MrDresden 3y ago
  "..recently found that there is some sort of frequency that may enhance / trigger the natural junk clearance mechanisms that go on during sleep.' I believe you are referencing [0], where scientists discovered that in mouse models the naturally occurring brainwaves generated during sleep help clean up extra cellular 'junk' in the brain via the glymphatic system. It has been known since 2012 that the glymphatic system (which was discovered around that time) was a mechanism for cleaning the brain. And even back then there was speculation around if Alzheimer patients had some kind of damage to this system which caused the build up of amyloid proteins. I have yet to see any research conducted on figuring that out (but it may exist). [0] https://jamanetwork.com/journals/jama/fullarticle/2816616 https://jamanetwork.com/journals/jama/fullarticle/2816616
wahnfrieden 3y ago
Even with this news, several in this thread are repeating that it's nothing special compared with influenza. People have turned off their minds to listen to culture war nonsense
LorenPechtel 3y ago
As far as I'm concerned the data has for a long time said that Covid typically causes lasting damage, it's just that for most people it's at a subclinical level. If this were not the case why do we see rising odds for Long Covid with repeated infections? If there's no lasting damage and it's facing a more tuned-in immune system the expected result would be a lower incidence. And we see athletes with higher rates of Long Covid than the population at large. Or do we? That could also be explained by athletes being more aware of where their limits are and are used to pushing themselves to those limits--hence they are more aware of impairment.

formvoltron 3y ago

Wow that's terrible. Well.. science has major incentive to find cures now. How many have long covid? Or maybe even subclinical long covid that may silently boost Alzheimer's risk? On a more positive note, they recently found that there is some sort of frequency that may enhance / trigger the natural junk clearance mechanisms that go on during sleep.

MrDresden 3y ago
"..recently found that there is some sort of frequency that may enhance / trigger the natural junk clearance mechanisms that go on during sleep.' I believe you are referencing [0], where scientists discovered that in mouse models the naturally occurring brainwaves generated during sleep help clean up extra cellular 'junk' in the brain via the glymphatic system. It has been known since 2012 that the glymphatic system (which was discovered around that time) was a mechanism for cleaning the brain. And even back then there was speculation around if Alzheimer patients had some kind of damage to this system which caused the build up of amyloid proteins. I have yet to see any research conducted on figuring that out (but it may exist). [0] https://jamanetwork.com/journals/jama/fullarticle/2816616 https://jamanetwork.com/journals/jama/fullarticle/2816616

wahnfrieden 3y ago

Even with this news, several in this thread are repeating that it's nothing special compared with influenza. People have turned off their minds to listen to culture war nonsense

LorenPechtel 3y ago

As far as I'm concerned the data has for a long time said that Covid typically causes lasting damage, it's just that for most people it's at a subclinical level. If this were not the case why do we see rising odds for Long Covid with repeated infections? If there's no lasting damage and it's facing a more tuned-in immune system the expected result would be a lower incidence. And we see athletes with higher rates of Long Covid than the population at large. Or do we? That could also be explained by athletes being more aware of where their limits are and are used to pushing themselves to those limits--hence they are more aware of impairment.