PFAS will mess you up. Badly. "How bad could they be?" You ask. "They're incredibly unreacitve!" Enter steric interference. Also, there's a very good reason

PFAS will mess you up. Badly. "How bad could they be?" You ask. "They're incredibly unreacitve!" Enter steric interference. Also, there's a very good reason we do animal studies; because, unless there's a really good reason why something (say burnt food -> we've coevolved with cooking) wouldn't affect humans, if it kills animals, it kills us.