There are issues for ones that don't use iLok or any bad DRM system at all. Kilohearts plugins, for example. 14.4 is bad, Apple makes it harder and harder to no

There are issues for ones that don't use iLok or any bad DRM system at all. Kilohearts plugins, for example. 14.4 is bad, Apple makes it harder and harder to not have your computer updated (including forcing major OS upgrades on users back in January and bypassing password authentication to do it, linked to multiple times here) and their software quality is not so good these days.