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Yes there was once a hype about these graphs and standards so called Resource Description Framework (RDF). It never took off. The knowledge itself requires heft
by dumb1224 3y ago
Yes there was once a hype about these graphs and standards so called Resource Description Framework (RDF). It never took off. The knowledge itself requires hefty curation though, if it's in a field that requires low false positive rate such as pharmacology.
- dvas 3y agoNot my area at all, just passing by and wondering to the extent and how they use knowledge graphs for drug discovery. Some time back I had a peek at AstraZeneca's GitHub [0] and got me curious. I know in genomics they try to use custom hardware to accelerate the process using FPGAs and others [1]. Curious if anyone can shed light on knowledge graph use at scale is being accelerated. [0] AstraZeneca; Awesome Drug Discovery Knowledge Graphs https://github.com/AstraZeneca/awesome-drug-discovery-knowledge-graphs https://github.com/AstraZeneca/awesome-drug-discovery-knowle... [1] Gene sequencing accelerates with custom hardware https://www.mewburn.com/news-insights/gene-sequencing-accelerates-with-custom-hardware https://www.mewburn.com/news-insights/gene-sequencing-accele...
- dumb1224 3y agoI only know in my area you can infer gene and protein interaction network using knowledge graphs to some degree. In drug discovery I've seen graphs of chemical knowledges and what can be drugged and what not. https://pubs.acs.org/doi/10.1021/acs.jpca.2c06408 https://pubs.acs.org/doi/10.1021/acs.jpca.2c06408 There might be more publications on mining literature and building such graphs but I'm not following it much since deep learning took over.