2 ms·

Look, astronomically few people are at baseline or zero risk for all ailments. Essentially everyone is genetically or environmentally predisposed to an increase

Look, astronomically few people are at baseline or zero risk for all ailments. Essentially everyone is genetically or environmentally predisposed to an increased relative risk of some many terrible things that could befall them in the future. Some people get to know about some of those biases ahead of time, some people don't get to know about them at all. This is now on your list. When you're in your seventies, and assuming continued research in this area doesn't refine in a way that excludes your case, you may be more likely to have dementia than some random person you know without ET. Relatively few people get diagnosed with dementia though, and that includes relatively few people with ET (although, apparently, more), so who really knows. Meanwhile, the rando that you picked to compare yourself to has their own known or unknown 3x risk for pancreatic cancer or aortic aneurism or kidney failure or something, and -- like you -- will probably not develop that particular condition anyway. This should not be read as "oh shit, I'm going to develop dementia because of this damned ET!" so much as "oh, well, I now know I should be extra attentive to early dementia symptoms in as I get older since ET might occasionally be associated with it"

d0mine 3y ago
The dementia rate is 25% at 80 and raises to 37% at 90.
- swatcoder 3y ago
  You know those numbers reflect survivor bias, right? By 80 and 90, most peers have already been lost to other organ failures, cancers, etc -- if longevity is important to them, most people would be lucky to be in those populations instead of the in much larger populations no longer being counted at all.
  - skissane 3y ago
    > By 80 and 90, most peers have already been lost to other organ failures, cancers, etc In many wealthy countries, life expectancy at birth is greater than 80, which means that the average 80 year old, >50% of their same-age peers will still be alive. By age 90, what you say would be true.

d0mine 3y ago

The dementia rate is 25% at 80 and raises to 37% at 90.

swatcoder 3y ago
You know those numbers reflect survivor bias, right? By 80 and 90, most peers have already been lost to other organ failures, cancers, etc -- if longevity is important to them, most people would be lucky to be in those populations instead of the in much larger populations no longer being counted at all.
- skissane 3y ago
  > By 80 and 90, most peers have already been lost to other organ failures, cancers, etc In many wealthy countries, life expectancy at birth is greater than 80, which means that the average 80 year old, >50% of their same-age peers will still be alive. By age 90, what you say would be true.