5 ms·
Truly excellent news… we’re now at 3 psychedelics given breakthrough designation by the FDA for different mental health indications: MDMA (ptsd), psilocybin (d
by radicaldreamer 3y ago
Truly excellent news… we’re now at 3 psychedelics given breakthrough designation by the FDA for different mental health indications:
MDMA (ptsd),
psilocybin (depression, anxiety),
LSD
There are startups testing 2CB, DMT and some more exotic psychedelics for various indications as well.
- j4hdufd8 3y agowhich startups?
- radicaldreamer 3y agoGood list here: https://psychedelicalpha.com/data/psychedelic-drug-development-tracker https://psychedelicalpha.com/data/psychedelic-drug-developme...
- tsoernes 3y agoThere's no mention of 2-CB in that list
- DoodahMan 3y agohttps://psychedelicalpha.com/wp-content/uploads/2023/02/Psychedelic-Drug-Development-Bullseye-Chart.pdf https://psychedelicalpha.com/wp-content/uploads/2023/02/Psyc... may be a better reference. for example, though not specified as 2C-B, Arcadia Medicine's AM-1002 (PTSD) is a phenethylamine.
- tomComb 3y agoIn this case it is a company called mind medicine.
- zoklet-enjoyer 3y agoMDMA isn't psychedelic. Or maybe I never took enough
- canadiantim 3y agoIt can be, for sure, but there's also so many different kinds that are sold as MDMA when it's actually a very similar but slightly different molecule.
- zoklet-enjoyer 3y agoBack in the day, I could get pure MDMA and several cathinones. I preferred methylone over MDMA
- devin 3y agoNot sure why you were downvoted. It’s well known that MDA is frequently sold as MDMA.
- drooby 3y agoIn my experience, it fits the definition. On higher doses of MDMA I experience mild to moderate closed eye hallucinations when listening to music (morphing shapes). Though I have never had open-eyed hallucinations to any degree. And I would absolutely define it as "consciousness expanding" in the sense that having conversations with friends while under its influence opens up aspects of my emotional mind that are very difficult for me to uncover while sober.
- canadiantim 3y agoDon't forget Ketamine. It's truly remarkable for depression and PTSD, arguably better than mdma or psilocybin because it's not as psychadelic but produces profound effects regardless. I took my mom to a ketamine clinic recently and up till then my biggest concern for her health was that she was always stuck in fight or flight, constant 11/10 stress levels, what I would call PTSD or complex PTSD. Anyway, after just 1 visit to ketamine clinic (2 low-medium dose sessions only), she's completely cured of her stress disorder. It's remarkable. This was a long-standing pattern for my mom and ketamine (with the help and guidance of an incredible therapist too) fixed it in a weekend, basically.
- noman-land 3y agoHow does it actually work? Ketamine is a tranquilizer, right? Is it like a therapy session you do using Ketamine to turn off your stress so you can think clearly? How does it have lasting effects?
- fragmede 3y agoI can't speak for GP, but when it's combined with talk therapy, the ketamine allows the body to lower its defenses so that talk therapy can more successfully be administered, and the combination of the two is what leads to long lasting effects, long after the ketamine has worn off. Ketamine let's the patient open up so talk therapy can get at the underlying issue and resolve that, in ways that talk therapy alone can't solve because the patient's flight /fight response/anxiety won't let them let their guard down to really talk about it.