3 ms·
News to me, so I went looking for more. This PubMed paper seems to back up what you've raised[0]: Conclusive Remarks As a final point, it appears important to
by meristohm 3y ago
News to me, so I went looking for more. This PubMed paper seems to back up what you've raised[0]:
Conclusive Remarks
As a final point, it appears important to stress that, although the majority of experimental studies have challenged cells or tissues with individual oxysterols, in the living organism oxysterols are present as mixtures, whether of endogenous or of exogenous origin. Like many other molecules with biochemical and/or pharmacological effects, oxysterols interact with one another in such a way as to modulate the effect of such mixtures. Quenching reactions among different components of oxysterol mixtures have been reported with regard to the role of oxysterols in atherosclerosis [46] and IBD progression [39].
Complex interactions of oxysterols likely occur in vivo, thus in vitro results concerning biochemical properties of pathologic amounts of individual oxysterols must be carefully weighed up and, where possible, accompanied and/or followed by analogous experiments with biologically compatible oxysterol mixtures.
[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757713/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757713/
- qwerty456127 3y agoLet me add a list of relevant links. I just hope this won't hit some filter as there are too many :-) I haven't read all of them, let alone thoroughly, but these are relevant research papers on the important subject we raised. [01] https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.2740550402 https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.2740550... [02] https://www.sciencedirect.com/science/article/abs/pii/S0140673687924433 https://www.sciencedirect.com/science/article/abs/pii/S01406... [03] https://www.academia.edu/80933160/High_Total_and_Cardiovascular_Disease_Mortality_in_Adults_of_Indian_Descent_in_Trinidad_Unexplained_by_Major_Coronary_Risk_Factors https://www.academia.edu/80933160/High_Total_and_Cardiovascu... [04] https://www.nature.com/articles/493S2a https://www.nature.com/articles/493S2a [05] https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.2740550402 https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.2740550... [06] https://www.nature.com/articles/493S2a https://www.nature.com/articles/493S2a [07] https://www.tandfonline.com/doi/abs/10.1080/07315724.1994.10718401 https://www.tandfonline.com/doi/abs/10.1080/07315724.1994.10... [08] https://pubmed.ncbi.nlm.nih.gov/27561087/ https://pubmed.ncbi.nlm.nih.gov/27561087/ [09] https://www.sciencedirect.com/science/article/pii/B9780128234211000020 https://www.sciencedirect.com/science/article/pii/B978012823... [10] https://pubmed.ncbi.nlm.nih.gov/24656052/ https://pubmed.ncbi.nlm.nih.gov/24656052/ [11] https://pubmed.ncbi.nlm.nih.gov/12531208/ https://pubmed.ncbi.nlm.nih.gov/12531208/ [12] https://pubmed.ncbi.nlm.nih.gov/25305550/ https://pubmed.ncbi.nlm.nih.gov/25305550/ [13] https://pubmed.ncbi.nlm.nih.gov/21388551/ https://pubmed.ncbi.nlm.nih.gov/21388551/ [14] https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/abs/effects-of-diets-rich-in-ghee-or-olive-oil-on-cardiometabolic-risk-factors-in-healthy-adults-a-twoperiod-crossover-randomised-trial/ED6B4C8EB745840BEDB44D8EA8F0F0D7 https://www.cambridge.org/core/journals/british-journal-of-n... [15] http://researcherslinks.com/current-issues/Effect-of-High-Dietary-Consumption-of-Locally/20/1/2741/html http://researcherslinks.com/current-issues/Effect-of-High-Di... [16] https://www.researchgate.net/publication/335421256_Biological_study_on_the_impact_of_commonly_used_commercial_fats_and_oil_and_threats_of_atherosclerosis https://www.researchgate.net/publication/335421256_Biologica... [17] https://pubmed.ncbi.nlm.nih.gov/11768237/ https://pubmed.ncbi.nlm.nih.gov/11768237/ [18] https://pubmed.ncbi.nlm.nih.gov/10718625/ https://pubmed.ncbi.nlm.nih.gov/10718625/ [19] https://pubmed.ncbi.nlm.nih.gov/20870006/ https://pubmed.ncbi.nlm.nih.gov/20870006/ [20] https://europepmc.org/article/agr/ind21989519 https://europepmc.org/article/agr/ind21989519 [21] https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.2740550402 https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.2740550... [22] https://pubmed.ncbi.nlm.nih.gov/4036336/ https://pubmed.ncbi.nlm.nih.gov/4036336/ [23] https://europepmc.org/article/agr/ind21989519 https://europepmc.org/article/agr/ind21989519 [24] https://cadiresearch.org/topic/diet-indian/animal-and-vegtable-ghee https://cadiresearch.org/topic/diet-indian/animal-and-vegtab... [25] https://www.jcpconline.org/article.asp?issn=2250-3528%3Byear%3D2017%3Bvolume%3D6%3Bissue%3D2%3Bspage%3D56%3Bepage%3D59%3Baulast%3DKhosla https://www.jcpconline.org/article.asp?issn=2250-3528%3Byear... [26] https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118534168.ch18 https://onlinelibrary.wiley.com/doi/abs/10.1002/978111853416... [27] https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118534168.ch18 https://onlinelibrary.wiley.com/doi/abs/10.1002/978111853416... [28] https://www.meneerspoor.nl/uploads/1/7/4/7/17471559/butter_pone.0158118.pdf https://www.meneerspoor.nl/uploads/1/7/4/7/17471559/butter_p... [39] https://pubmed.ncbi.nlm.nih.gov/27561087/ https://pubmed.ncbi.nlm.nih.gov/27561087/ [30] https://www.researchgate.net/publication/26523948_Cholesterol_oxidized_products_in_foods_Potential_health_hazards_and_the_role_of_antioxidants_in_prevention https://www.researchgate.net/publication/26523948_Cholestero... [31] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931501/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931501/ [32] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121705/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121705/