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The Science Behind Ozempic Was Wrong

• turadg 3y ago
  The weight-loss effects of GLP-1 drugs have little to do with the gut. https://web.archive.org/web/20240305193736/https://www.theatlantic.com/health/archive/2024/03/ozempic-glp1-weight-loss-brain-gut/677645/ https://web.archive.org/web/20240305193736/https://www.theat...
  • toomuchtodo 3y ago
    In hindsight, this is somewhat obvious due to the anti addiction properties of GLP-1 agonists.
  • glp1guide 3y ago
    Wow this is a fascinating thesis -- GLP1 was known to affect the stomach AND the brain, and it certainly does affect the stomach, but for the weight loss properties to be simply brain-driven might be a bit simplistic. It certainly does explain the effects on other kinds of addictive behavior, but that effect is less supported by research (that I can find, anyway).
    • chapulin 3y ago
      There’s some pretty compelling research on the brain effects. Here’s a quick explainer: https://youtu.be/dCm6QLGnPPw?si=-OlxcXp8mRBHlCo7 https://youtu.be/dCm6QLGnPPw?si=-OlxcXp8mRBHlCo7