>This is how allergy treatments work. But allergens are not pathogens, we are looking at substantially different immune pathways and function (allergens have n

>This is how allergy treatments work. But allergens are not pathogens, we are looking at substantially different immune pathways and function (allergens have no lifecycle, let alone one involving host cells). >Apparently some infections (at least dengue) are worse the second time. There is some compelling evidence to suggest it is specifically having a low, but not zero, level of antibodies that paradoxically increases the chance of severe infection in dengue fever specifically. Possibly by enhancing dengue's ability to infiltrate cells when it is only slightly coated with antibodies [1]. So even in this rather unusual case, it is not seeing dengue a lot, but rather seeing it exactly once and then seeing it again after several years without any contact that appears to cause this issue. [1] - https://www.statnews.com/2017/11/02/dengue-second-infection/ https://www.statnews.com/2017/11/02/dengue-second-infection/