I would like to build image labeling tools with bounding boxes and pixelwise segmentations. Ideally it would support 16bit grayscale medical image. As a stretch

I would like to build image labeling tools with bounding boxes and pixelwise segmentations. Ideally it would support 16bit grayscale medical image. As a stretch goal it would support 3d stacks of image for a CT or MR. This is obivously too much to ask, but I would like to have a way to build it. It would require some sort of custom frondend events making it to the back end.