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The CDC is saying it's okay to infect other people because pretty much everyone on earth has already been infected with the novel sars-cov-2 virus and taken the

The CDC is saying it's okay to infect other people because pretty much everyone on earth has already been infected with the novel sars-cov-2 virus and taken their risk already with the first infection. Anyone that would have bad outcomes has died or been taken out of productive life so they don't matter. And the rare few of us that have still avoided any exposure to sars-cov-2 virus in our upper respiratory mucosal immune compartment don't matter because we are so few and the humoral immune compartment is protected by intramuscular vaccination. A very pragmatic position but not one that has much to do with the science of sars-cov-2 shed duration or infective window.

johnnyanmac 3y ago
>And the rare few of us that have still avoided any exposure to sars-cov-2 virus in our upper respiratory mucosal immune compartment don't matter because we are so few and the humoral immune compartment is protected by intramuscular vaccination. As one of the rare few, I'd rather not take risks, especially since there's still so much developing science behind the long term effects of COVID. Good to know the CDC does not in fact care about disease control for those who heeded their advice up until now.
SideburnsOfDoom 3y ago
> Anyone that would have bad outcomes has died or been taken out of productive life so they don't matter. That's just not how it works though. Each subsequent infection increases the risk of bad outcomes (1) The CDC must know this 1) https://www.unmc.edu/healthsecurity/transmission/2023/12/27/every-covid-infection-increases-your-risk-of-long-covid-study-warns https://www.unmc.edu/healthsecurity/transmission/2023/12/27/... https://time.com/6553340/covid-19-reinfection-risk/ https://time.com/6553340/covid-19-reinfection-risk/ https://www.theguardian.com/world/2023/jan/23/repeat-covid-infections-health-risks https://www.theguardian.com/world/2023/jan/23/repeat-covid-i...
- superkuh 3y ago
  True enough. I didn't want to complicate my message. I only meant the risk of the first exposure is much, much greater than subsequent ones. It is unarguable that the risk of the first exposure to a novel virus is much greater than subsequent exposures. I say this because T-cells generalize across mutations. And T-cells stay tissue resident for years to decades (unfortunately sars-cov-2 IgG and IgA antibodies are gone by 6 months). Your T-cells from the first sars-cov-2 exposure will start killing infected cells much faster once you've been exposed. This limits the replication earlier and reduces the viral load. This reduces damage done. Weird side effects like the collection of things called long-covid have been shown in study after study not to be related to viral load. So whatever risk is associated with reinfection does not decrease in that sense. But in the dying sense? It decreases a lot.
  - gnicholas 3y ago
    > I only meant the risk of the first exposure is much, much greater than subsequent ones. I have heard of some people whose second case of COVID (Dec 2023) was significantly worse than their first (summer 2022). This might be due to the amount of time since last vaccination, or the amount of exposure to an infected person. But I was interested to hear from a couple friends that the second time isn't always lighter than the first.
    - superkuh 3y ago
      This is not mutually exclusive with what I have said. The risk is greater in the first infection. It does not mean risk goes away with subsequent infections.
lurking15 3y ago
> The CDC is saying it's okay to infect other people because pretty much everyone on earth has already been infected with the novel sars-cov-2 virus and taken their risk already with the first infection. Spreading respiratory viruses is really called living in a normal human society, and for whatever reason medical professions abandoned every conventional advice and emergency plan of the past that was prepared for responding to novel respiratory contagious disease of the sort a coronavirus would be, that spares the vast majority of healthy people, and resorted to what I call Open Air Surveillance Fascism. I'll never forget the absurdity of healthy people on a beach, which was probably the safest thing a person could do with maximum ventilation and full sunlight, with some moron shaming everyone while dressed in a reaper outfit.

johnnyanmac 3y ago

>And the rare few of us that have still avoided any exposure to sars-cov-2 virus in our upper respiratory mucosal immune compartment don't matter because we are so few and the humoral immune compartment is protected by intramuscular vaccination. As one of the rare few, I'd rather not take risks, especially since there's still so much developing science behind the long term effects of COVID. Good to know the CDC does not in fact care about disease control for those who heeded their advice up until now.

SideburnsOfDoom 3y ago

> Anyone that would have bad outcomes has died or been taken out of productive life so they don't matter. That's just not how it works though. Each subsequent infection increases the risk of bad outcomes (1) The CDC must know this 1) https://www.unmc.edu/healthsecurity/transmission/2023/12/27/every-covid-infection-increases-your-risk-of-long-covid-study-warns https://www.unmc.edu/healthsecurity/transmission/2023/12/27/... https://time.com/6553340/covid-19-reinfection-risk/ https://time.com/6553340/covid-19-reinfection-risk/ https://www.theguardian.com/world/2023/jan/23/repeat-covid-infections-health-risks https://www.theguardian.com/world/2023/jan/23/repeat-covid-i...

superkuh 3y ago
True enough. I didn't want to complicate my message. I only meant the risk of the first exposure is much, much greater than subsequent ones. It is unarguable that the risk of the first exposure to a novel virus is much greater than subsequent exposures. I say this because T-cells generalize across mutations. And T-cells stay tissue resident for years to decades (unfortunately sars-cov-2 IgG and IgA antibodies are gone by 6 months). Your T-cells from the first sars-cov-2 exposure will start killing infected cells much faster once you've been exposed. This limits the replication earlier and reduces the viral load. This reduces damage done. Weird side effects like the collection of things called long-covid have been shown in study after study not to be related to viral load. So whatever risk is associated with reinfection does not decrease in that sense. But in the dying sense? It decreases a lot.
- gnicholas 3y ago
  > I only meant the risk of the first exposure is much, much greater than subsequent ones. I have heard of some people whose second case of COVID (Dec 2023) was significantly worse than their first (summer 2022). This might be due to the amount of time since last vaccination, or the amount of exposure to an infected person. But I was interested to hear from a couple friends that the second time isn't always lighter than the first.
  - superkuh 3y ago
    This is not mutually exclusive with what I have said. The risk is greater in the first infection. It does not mean risk goes away with subsequent infections.

lurking15 3y ago

> The CDC is saying it's okay to infect other people because pretty much everyone on earth has already been infected with the novel sars-cov-2 virus and taken their risk already with the first infection. Spreading respiratory viruses is really called living in a normal human society, and for whatever reason medical professions abandoned every conventional advice and emergency plan of the past that was prepared for responding to novel respiratory contagious disease of the sort a coronavirus would be, that spares the vast majority of healthy people, and resorted to what I call Open Air Surveillance Fascism. I'll never forget the absurdity of healthy people on a beach, which was probably the safest thing a person could do with maximum ventilation and full sunlight, with some moron shaming everyone while dressed in a reaper outfit.