3 ms·
An A is replaced by a T, or by a G, or by a C, or vice versa. The more expansive side of the coin are indels or CNVs (copy number variations), where pieces of
by a_bonobo 3y ago
An A is replaced by a T, or by a G, or by a C, or vice versa.
The more expansive side of the coin are indels or CNVs (copy number variations), where pieces of genome are replaced by other pieces (ATGCT by ATGCTCTA for example) or just deleted, or where specific pieces are copied a few times. These are far harder to measure using current sequencing technologies; most people still use the ubiquitous Illumina machines which can go up to 300bp, and we know many of those more complex mutations are longer than that.