What you're describing is fairly close to Intel's Beast Canion NUC [0] from a couple of years back. The Mobo and GFX essentially sit back to back. Though intel

What you're describing is fairly close to Intel's Beast Canion NUC [0] from a couple of years back. The Mobo and GFX essentially sit back to back. Though intel seemed to envisage upgrading the whole "CPU side" as a single piece (including ram) which probably, along with its high price, put off buyers. Following on from that though, there are a number of miniitx cases that followed on from that type of layout such as the fractal terra [1] which utilize a pcie riser to pass it rearward to the graphics card behind the motherboard. ATX/ITX wasn't entirely designed for it, but the layout does seem to be quite elegant. [0] https://www.tomshardware.com/reviews/nuc-11-extreme-kit-beast-canyon https://www.tomshardware.com/reviews/nuc-11-extreme-kit-beas... [1] https://www.fractal-design.com/products/cases/terra/terra/terra-jade/ https://www.fractal-design.com/products/cases/terra/terra/te...