3 ms·

"I would receive no ‘direct benefits’ from the study – except for $4,875 in cash." They don't cover related medical treatment for adverse events?

captainkrtek 3y ago
I believe not. I was part of a phase 1 clinical study for a vaccine, and I recall asking a question along these lines. They mentioned some medical care may be covered, but otherwise not. This was a few years ago so I could be mistaken.
- lamontcg 3y ago
  Yeah so they're mostly seeking people who are willing to trade a small risk of some horrible lifelong autoimmune condition for $5k right now. Not surprising two of the other guys in the study have been to prison. Either human challenge trials should not reimburse at all, and seek the true believers in it, or they should cover all future medical bills for any chronic immune conditions that emerge in the next 3 months (and just one of those outcomes probably blows up the economic utility of challenge trials).
  - captainkrtek 3y ago
    I took the risk not for the money (about 5k over a year) but for a genuine interest, also this was for a covid vaccine during the pandemic, so figured some folks need to volunteer..
refurb 3y ago
Oh they absolutely do. That a requirement of all human studies. That said, it can be challenging proving your medical problem is due to the intervention. But all patients need to be followed up for measures of safety and any adverse event need to be paid for by the sponsor.
RobAley 3y ago
(Source : I work in vaccine research, including challenge studies, in the UK, but only in IT/Digital, I'm not clinical). In the UK at least (and as I understand it in most countries that subscribe to the principles of the Declaration of Helsinki), all of our studies have to have insurance to cover such eventualities (which are exceedingly rare these days). In addition, we provide clinical contacts for the participants throughout the trial and follow-up, and ensure that participant NHS medical records (and central NHS databases such as for the COVID vaccines) are updated with the necessary details for any future related care. Money/Payment is always a careful balance. You don't want people taking part in the trials purely for the money (i.e. doing something they wouldn't otherwise be comfortable doing), but you need to ensure they aren't disadvantaged by taking part in the trial.

captainkrtek 3y ago

I believe not. I was part of a phase 1 clinical study for a vaccine, and I recall asking a question along these lines. They mentioned some medical care may be covered, but otherwise not. This was a few years ago so I could be mistaken.

lamontcg 3y ago
Yeah so they're mostly seeking people who are willing to trade a small risk of some horrible lifelong autoimmune condition for $5k right now. Not surprising two of the other guys in the study have been to prison. Either human challenge trials should not reimburse at all, and seek the true believers in it, or they should cover all future medical bills for any chronic immune conditions that emerge in the next 3 months (and just one of those outcomes probably blows up the economic utility of challenge trials).
- captainkrtek 3y ago
  I took the risk not for the money (about 5k over a year) but for a genuine interest, also this was for a covid vaccine during the pandemic, so figured some folks need to volunteer..

refurb 3y ago

Oh they absolutely do. That a requirement of all human studies. That said, it can be challenging proving your medical problem is due to the intervention. But all patients need to be followed up for measures of safety and any adverse event need to be paid for by the sponsor.

RobAley 3y ago

(Source : I work in vaccine research, including challenge studies, in the UK, but only in IT/Digital, I'm not clinical). In the UK at least (and as I understand it in most countries that subscribe to the principles of the Declaration of Helsinki), all of our studies have to have insurance to cover such eventualities (which are exceedingly rare these days). In addition, we provide clinical contacts for the participants throughout the trial and follow-up, and ensure that participant NHS medical records (and central NHS databases such as for the COVID vaccines) are updated with the necessary details for any future related care. Money/Payment is always a careful balance. You don't want people taking part in the trials purely for the money (i.e. doing something they wouldn't otherwise be comfortable doing), but you need to ensure they aren't disadvantaged by taking part in the trial.