The commonality between manic depression and ADHD is low serotonin up take. The primary role of serotonin is mood regulation, but the consequences of poor mood

The commonality between manic depression and ADHD is low serotonin up take. The primary role of serotonin is mood regulation, but the consequences of poor mood regulation are complex even if the problem is simple. Converse that against dopamine deficiency which is a complex problem with limited consequences that plagues ADHD but not so much manic depression. Low serotonin can result in metabolic inefficiencies which means poor body temperature and/or weight gain/loss out of norm even with a perfect diet. Over correcting with too much serotonin results in different mood irregularities like nightmares and anxiety and more. The primary limitation with these problems, aside from metabolic issues, are poor decision skills that in isolation are either prematurely considered or too emotionally weighted.