Yep. If you were a gaming PC motherboard PCB manufacturer needing 8 layers, blind micro vias, and G-code output for drilling, good luck with that using anything

Yep. If you were a gaming PC motherboard PCB manufacturer needing 8 layers, blind micro vias, and G-code output for drilling, good luck with that using anything but those enterprise EDA suites mentioned. EDA users exist along multiple dimensions including level of detail, subassembly/mechanical/BOM management, customizability, system/signal simulation/verification, automation, learning curve, and cost.