2 ms·
> man in his 40s who developed manic and psychotic symptoms temporally after receiving his first Moderna/Spikevax bivalent COVID-19 vaccine ... He previously re
by walterbell 3y ago
> man in his 40s who developed manic and psychotic symptoms temporally after receiving his first Moderna/Spikevax bivalent COVID-19 vaccine ... He previously received three doses of the Pfizer-BioNTech/Comirnaty vaccine with no significant side effects ... he was hospitalized and treated with Olanzapine, after which his symptoms resolved.
> Clinicians should be alert to the possibility of patients developing neuropsychiatric complications post-SARS-CoV-2 vaccination ... Possible underlying mechanisms may involve mRNA vaccines triggering autoimmune responses and proinflammatory reactions, leading to neuropsychiatric symptoms ... There is a need to systematically collect data on the neuropsychiatric side effects of having COVID-19 booster vaccines in order to develop a standardised clinical framework that can be used internationally for patient safety as well as to guide healthcare policy decision-making.
- gus_massa 3y agoIf it's a single case, there is a high chance that it's just a unlucky coincidence.
- walterbell 3y agoHence the call for more data collection. Linked from this paper: 2021, "Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection", https://www.nature.com/articles/s41591-021-01556-7 https://www.nature.com/articles/s41591-021-01556-7 > Overall, we estimated 38 excess cases of Guillain–Barré syndrome per 10 million people receiving ChAdOx1nCoV-19 and 145 excess cases per 10 million people after a positive SARS-CoV-2 test. 2022, "Psychosis Associated With COVID-19 Vaccination", https://www.psychiatrist.com/pcc/psychosis-associated-covid-19-vaccination/ https://www.psychiatrist.com/pcc/psychosis-associated-covid-... > There are case reports of various psychiatric symptoms in both psychiatric patients and patients with no history of psychiatric illnesses following COVID-19 infection that include manic-like symptoms, insomnia, brief reactive psychotic disorders, affective psychosis, suicide, and delirium. A review of the impact of the COVID-19 epidemic estimated that 0.9%–4% of COVID-19–infected individuals develop psychotic spectrum disorders. This report describes a case of psychosis associated with COVID-19 vaccination and superimposed COVID-19 infection.